The Ongoing Genetic Adaptation of Streptococcus pneumoniae.

Richter SS1, Musher DM2.

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Abstract

Streptococcus pneumoniae has demonstrated a remarkable ability to adapt during the conjugate vaccine era. The increasing incidence of serotype 35B disease and emergence of a multidrug-resistant clone reported in this issue of the Journal of Clinical Microbiology (L. Olarte et al., J Clin Microbiol 55:724-734, 2017, https://doi.org/10.1128/JCM.01778-16) underscore the limitations of pneumococcal vaccines that target the polysaccharide capsule.

Copyright © 2017 American Society for Microbiology.

PMID: 27974545 PMCID: PMC5328434