J Clin Microbiol. 2017 Mar;55(3):776-782. doi: 10.1128/JCM.02405-16. Epub 2016 Dec 14.

Nosocomial Outbreak of Drug-Resistant Streptococcus pneumoniae Serotype 9V in an Adult Respiratory Medicine Ward.

Jauneikaite E1,2, Khan-Orakzai Z3, Kapatai G4, Bloch S3, Singleton J3, Atkin S5, Shah V5, Hatcher J3, Samarasinghe D3, Sheppard C4, Fry NK4, Satta G6,7, Sriskandan S8,2.

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Abstract

Streptococcus pneumoniae infections arising in hospitalized patients are often assumed to be sporadic and linked to community acquisition. Here, whole-genome sequencing was used to demonstrate nosocomial acquisition of antimicrobial-resistant sequence type 156 (ST156) serotype 9V S. pneumoniae in 3 respiratory patients that resulted in two bacteremias and one lower respiratory tract infection. Two of the cases arose in patients who had recently been discharged from the hospital and were readmitted from the community. Nosocomial spread was suspected solely because of the highly unusual resistance pattern and case presentations within 24 h of one another. The outbreak highlights the potential for rapid transmission and the short incubation period in the respiratory ward setting.

Copyright © 2017 Jauneikaite et al.

KEYWORDS:

Streptococcus pneumoniae; bacteremia; nosocomial infections; pneumonia; serotype 9V

PMID: 27974539 PMCID: PMC5328445