Future Microbiol. 2016 May 18. [Epub ahead of print]

Prevalence and antibiotic resistance of commensal Streptococcus pneumoniae in nine European countries.

Yahiaoui RY1,2, den Heijer CD1, van Bijnen EM3, Paget WJ3,4, Pringle M5, Goossens H6, Bruggeman CA1, Schellevis FG3,7, Stobberingh EE1;APRES Study Team.

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Abstract

The human microbiota represents an important reservoir of antibiotic resistance. Moreover, the majority of antibiotics are prescribed in primary care. For this reason, we assessed the prevalence and antibiotic resistance of nasal carriage strains of Streptococcus pneumoniae, the most prevalent bacterial causative agent of community-acquired respiratory tract infections, in outpatients in nine European countries. Nasal swabs were collected between October 2010 and May 2011, from 32,770 patients, recruited by general practices in nine European countries. Overall prevalence of S. pneumoniae nasal carriage in the nine countries was 2.9%. The carriage was higher in men (3.7%) than in women (2.7%). Children (4-9 years) had a higher carriage prevalence (27.2%) compared with those older than 10 years (1.9%). The highest resistance observed was to cefaclor. The highest prevalence of multidrug resistance was found in Spain and the lowest prevalence was observed in Sweden.

KEYWORDS:

Streptococcus pneumoniae; antibiotic resistance; nasal swab

PMID: 27191588 [PubMed - as supplied by publisher]