J Microbiol Immunol Infect. 2015 Sep 9. pii: S1684-1182(15)00832-4. doi: 10.1016/j.jmii.2015.08.009. [Epub ahead of print]

The effect of immunization with pneumococcal conjugated vaccines onStreptococcus pneumoniae resistance patterns in acute otitis media.

Marom T1, Avraham E2, Cinamon U1, Tamir SO3.

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Following the introduction of 7- and 13-pneumococcal conjugate vaccines (PCVs) in Israel, we demonstrated that within Streptococcus pneumoniae (Sp) positive middle ear cultures, obtained from young children with severe acute otitis media (AOM) episodes, there were more penicillin-susceptible and less multi-drug resistant Sp isolates in PCV immunized children.

Copyright © 2015. Published by Elsevier B.V.


Streptococcus pneumoniae; acute otitis media; antibiotic resistance; pneumococcal conjugate vaccine

PMID: 26507672 [PubMed - as supplied by publisher]