Lupus. 2015 Oct 8. pii: 0961203315611498. [Epub ahead of print]

Streptococcus pneumoniae necrotizing fasciitis in systemic lupus erythematosus.

Sánchez A1, Robaina R1, Pérez G1, Cairoli E2.

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Necrotizing fasciitis is a rapidly progressive destructive soft tissue infection with high mortality.Streptococcus pneumoniae as etiologic agent of necrotizing fasciitis is extremely unusual. The increased susceptibility to Streptococcus pneumoniae infection in patients with systemic lupus erythematosus is probably a multifactorial phenomenon. We report a case of a patient, a 36-year-old Caucasian female with 8-year history of systemic lupus erythematosus who presented a fatal Streptococcus pneumoniaenecrotizing fasciitis. The role of computed tomography and the high performance of blood cultures for isolation of the causative microorganism are emphasized. Once diagnosis is suspected, empiric antibiotic treatment must be prescribed and prompt surgical exploration is mandatory.

© The Author(s) 2015.


Streptococcus pneumoniae; infection; necrotizing fasciitis; systemic lupus erythematosus

PMID: 26453662 [PubMed - as supplied by publisher]