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The van Opijnen Lab


LATEST NEWS

July 2017 - Graduate student Karen Zhu and former Postdoc Paul Jensen share a first author paper in Cell Reports! We are all super excited about this great accomplishment! Karen and Paul are publishing the first metabolic model for Streptococcus pneumoniae and show how integration of genome-wide data with topological network analysis reveals how a bacterium responds to stress. Surprisingly, they show that different transcriptional and phenotypic response networks exist in bacteria and how this undermines the widely held assumption that genes that change in expression upon an environmental disturbance must also phenotypically matter. More to follow soon...

June 2017 - We welcome Dr. Bimal Jana as a postdoctoral fellow to the lab!

May 2017 - Former undergraduates Katherine McCoy and Margaret Antonio (currently graduate students at Dartmouth and Stanford) got a first-authored paper with Dr. van Opijnen accepted at the journal Bioinformatics!

May 2017 - Lauren Havens received an ASM Undergraduate Research Fellowship!

May 2017 - Undergraduates Sophie Bodrog, Anas Beshir, Camille Homa and Allison Chowdhury all received an Undergradute Research Summer Felllowship from Boston College!

April 2017 - Dr. van Opijnen has been promoted to Associate Professor!

March 2017 - Defne Surujon has joined the lab as a graduate student!

January 2017 - Happy New Year! And we welcome Dr. Juance Ortiz-Marquez from Argentina to the lab!

November 2016 - Super interesting article about our work on statnews.com describing how we are working towards predicting the emergence of antimicrobial resistance.

SCROLL DOWN

The van Opijnen Lab


LATEST NEWS

July 2017 - Graduate student Karen Zhu and former Postdoc Paul Jensen share a first author paper in Cell Reports! We are all super excited about this great accomplishment! Karen and Paul are publishing the first metabolic model for Streptococcus pneumoniae and show how integration of genome-wide data with topological network analysis reveals how a bacterium responds to stress. Surprisingly, they show that different transcriptional and phenotypic response networks exist in bacteria and how this undermines the widely held assumption that genes that change in expression upon an environmental disturbance must also phenotypically matter. More to follow soon...

June 2017 - We welcome Dr. Bimal Jana as a postdoctoral fellow to the lab!

May 2017 - Former undergraduates Katherine McCoy and Margaret Antonio (currently graduate students at Dartmouth and Stanford) got a first-authored paper with Dr. van Opijnen accepted at the journal Bioinformatics!

May 2017 - Lauren Havens received an ASM Undergraduate Research Fellowship!

May 2017 - Undergraduates Sophie Bodrog, Anas Beshir, Camille Homa and Allison Chowdhury all received an Undergradute Research Summer Felllowship from Boston College!

April 2017 - Dr. van Opijnen has been promoted to Associate Professor!

March 2017 - Defne Surujon has joined the lab as a graduate student!

January 2017 - Happy New Year! And we welcome Dr. Juance Ortiz-Marquez from Argentina to the lab!

November 2016 - Super interesting article about our work on statnews.com describing how we are working towards predicting the emergence of antimicrobial resistance.

The van Opijnen Lab practices microbial systems biology which basically means that we try to understand a bacterium as a complete system. So instead of carefully studying the organism one component at the time we build networks of all the genetic elements that drive a bacterium's behavior. Thereby we rapidly develop a real good understanding of how a bacterium does its thing, for instance trigger disease.

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Our work


We mainly focus on pathogenic bacteria and apply a combination of high-throughput robotics, next generation sequencing and computational biology to discover what makes them tick.

Our work


We mainly focus on pathogenic bacteria and apply a combination of high-throughput robotics, next generation sequencing and computational biology to discover what makes them tick.

The van Opijnen Lab focuses on projects to determine how bacteria trigger disease on a genome-wide level and species-wide scale, we elucidate the fine inner workings of antibiotics and we develop new genome-wide tools and screens to identify novel antimicrobial compounds.

More research

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The Lab


The Lab


Tim van opijnen

Principal Investigator

Dr van Opijnen received his Masters in evolutionary genetics from the University of Amsterdam, and as a graduate student he worked on the evolution of HIV at the Medical School of the University of Amsterdam. As a postdoctoral fellow in the lab of Dr. Andrew Camilli at Tufts University in Boston his interests shifted to bacterial pathogens and systems biology. Since January 2013 he runs his own lab as an Assistant Professor of Microbial Systems Biology at Boston College.

The workers

Postdocs & Grad students

Check out the PEOPLE for more information on who's who in the lab. If you are interested in joining the lab as a postdoc, grad student or technician, check-out the JOBS page for possible openings.

 

The Rookies

Undergraduates

We house a large flock of undergraduate students on the computational and wet-bench side of the lab. Each undergraduate works in close collaboration with a postdoc or graduate student. If you are interested in joining the lab as an undergraduate student please send an inquiry email including your CV to Dr. van Opijnen.

A production of Boston College Magazine's @BC Studio

Produced by Ravi Jain